Best NFL prop bets for Panthers vs. Titans in Week 12 (Trust DeAndre Hopkins)

Betting odds, pick and best prop bets for Sunday's Week 12 contest between the Carolina Panthers and the Tennessee Titans.

Tennessee Titans wide receiver DeAndre Hopkins (10) hauls in a reception for a touchdown score
Tennessee Titans wide receiver DeAndre Hopkins (10) hauls in a reception for a touchdown score / Corey Perrine/Florida Times-Unio / USA
facebooktwitterreddit

Will Levis and the Tennessee Titans welcome Bryce Young and the Carolina Panthers to Nissan Stadium in a battle between QBs from the 2023 NFL Draft

I found two Titans props involving DeAndre Hopkins and Derrick Henry, along with a Panthers prop that seems like a lock.

If you want to see where I found these player props, check out DraftKings Sportsbook, where new users will receive $150 in bonus bets and no-sweat game parlays when they bet $5. 

Best NFL Prop Bets for Panthers vs. Titans in Week 12

  • DeAndre Hopkins OVER 56.5 receiving yards (-120)
  • Derrick Henry OVER 67.5 rushing yards (-115)
  • Chuba Hubbard UNDER 15.5 receiving yards (-120)

DeAndre Hopkins OVER 56.5 receiving yards (-120)

Veteran wide receiver DeAndre Hopkins has become Will Levis’ favorite receiving target since his debut in Week 8 against the Falcons. Hopkins has recorded 15 receptions (31 targets) for 274 yards and four touchdowns in the Titans’ last four games. 

Within those four games, the veteran wideout has gone OVER 56.5 receiving yards three times. The 31-year-old will try to add to his receiving yards total against a Panthers’ defense that’s ranked 26th in DVOA-WR1, per ftnfantasy.com. They’ve also allowed 70.2 yards per game to WR1s this season. 

Derrick Henry OVER 67.5 rushing yards (-115)

The star running back has had a ton of vintage moments this season, but that could change on Sunday afternoon against the Panthers. This season, Carolina’s defense has struggled to stop the run, giving up 129.4 yards per game (24th in the NFL). 

The Panthers’ defense has played better lately, allowing 106 rushing yards per game in their last three games. However, there’s something to be said about Carolina giving up 146 rushing yards per game on the road.

Henry has only gone OVER 67.5 rushing yards in five out of his last 10 games. King Henry is also averaging 100 rushing yards per game at home. Don’t give up on the future Hall of Fame running back yet.

Chuba Hubbard UNDER 15.5 receiving yards (-120)

The advanced metrics say that Panthers RB Chuba Hubbard should thrive in the passing game against the Titans, who are ranked 26th in DVOA-RB, per ftnfantasy.com. However, Tennessee allows the fifth-fewest receiving yards per game to running backs (24.9).

Hubbard has gone UNDER 15.5 receiving yards in seven out of his last 10 games. He’s also started in the Panthers’ last five games but only averaging 2.2 receptions for 12.2 yards per game.


Game odds refresh periodically and are subject to change.