Titans Game Sunday: Titans vs Colts odds and prediction for NFL Week 3 game

Tennessee Titans. (Photo by Andy Lyons/Getty Images)
Tennessee Titans. (Photo by Andy Lyons/Getty Images) /
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The Tennessee Titans will take on the Indianapolis Colts in their first division rivalry matchup of the 2021 season. The last time these two teams met was in November of 2020 when the Titans won 45-26.

Both Tennessee and Indianapolis finished with 11-5 records in the AFC South last season, but Tennessee won the division due to a division record tiebreaker.

This year, the Titans’ starting lineup will be led by Ryan Tannehill, who will face a new challenger in Colts’ quarterback Carson Wentz.

Titans vs Colts Odds Week 3

The Week 3 betting odds on WynnBET has Tennessee as 5-point favorites at home. They have -255 moneyline odds, while Indianapolis is the underdog at +200. The total for the game is set at an over/under of 50 points.

Titans vs Colts Prediction Week 3

Tennessee is coming off their first win of the season, while the Colts have yet to win a game in 2021. Their offense saw good production from Julio Jones and yet another amazing performance from Derrick Henry, who posted 182 rushing yards and three touchdowns.

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Given the Colts’ leaky secondary of late, it appears that they can be in both the running and passing game. Henry recently broke records as the fourth player in NFL history with 10 career games recording at least 150 rushing yards and two rushing touchdowns.

He will be just as explosive against Indy’s defensive line this week, and we’re predicting a 28-24 victory for the home team.

Make your pick now on WynnBET.