Titans Game Sunday: Titans vs Arizona odds and prediction for NFL Week 1 game

Derrick Henry, Tennessee Titans (Photo by Christian Petersen/Getty Images)
Derrick Henry, Tennessee Titans (Photo by Christian Petersen/Getty Images) /

Games like these are why we watch the NFL. The Tennessee Titans and Arizona Cardinals meet in Week 1 of the 2021 NFL season at Nissan Stadium, and for both franchises, this one serves as an opportunity to get off to a great start in 2021 after the 2020 season didn’t turn out the way either side wanted.

The Titans entered the 2020 season looking to make good on some unfinished business. They ended the 2019-2020 NFL season with an AFC Championship Game loss to the eventual Super Bowl Champions, the Kansas City Chiefs. A year ago, they won the AFC South but were bounced in the first round by the Baltimore Ravens. Hopefully, this year, they put it all together.

The Cards are looking to catapult themselves into the NFC’s upper echelon, something that hasn’t happened in either of Kliff Kingsbury’s first two seasons at the helm. Playing in what’s arguably the NFL’s best division, the NFC West, may have something to do with that, but Arizona has no excuse.

They’re loaded with stars on both sides of the ball as are the Titans. This one’s going to be two tons of fun.

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Titans vs Arizona Odds Week 1

The Week 1 odds on WynnBET have the Titans as three-point favorites at the friendly confines of Nissan Stadium. They have -150 moneyline odds, while Arizona is the underdog at +130. The total for the game is set at an over/under of 52 points.

Titans vs Arizona Prediction Week 1

Based on what we’re seeing the over/under and the moneyline appear to be accurate. Both teams can light it up. We can expect some defensive mistakes as that can be common in Week 1, but in the end, expect Tennessee to come out on top.

This one will end in a 31-24 win by the Titans. Arizona will keep this close throughout the game, making for an uneasy experience, but the Titans will outlast them, run some clock with Derrick Henry late, and finish things in the victory formation with Ryan Tannehill kneeling three times.

Make your pick now on WynnBET.

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